1/ Introduction
Polyvinyl Alcohol, commonly known as PVA, is an excipient widely used in various pharmaceutical formulation and manufacturing applications, most notably as a film-forming agent in moisture-protective coated tablets. PVA helps reduce water vapor absorption, protect moisture-sensitive active ingredients, and maintain the stability of the dosage form.
2/ Key Advantages
- Non-ionic polymer, thus it does not interact with active pharmaceutical ingredients.
- Forms a protective film coating that serves as a moisture and gas barrier, providing an elegant appearance and excellent adhesion to tablet cores, thereby minimizing the risk of film peeling or logo bridging.
- Low viscosity allows for a high solid content in the coating dispersion (up to 20%), improving coating efficiency and reducing processing time.
- Freely soluble in water.
- Studies have demonstrated that PVA exhibits lower water vapor permeability compared to HPMC, providing superior moisture protection for hygroscopic or moisture-sensitive drugs.
- Moisture-protective coatings using PVA do not affect drug release profiles.
- Flexible in formulation development and offers easier control over raw material sourcing compared to ready-to-use coating systems.
- Product complies with USP/EP/BP
- The manufacturer has EXCIPACT GMP Certificate for Pharma application
- Stock available at GSP/ GDP warehouse, prompt delivery, competitive price
3/ Applications
- Film-forming agent providing moisture protection for coated tablets.
- Binding agent for wet granulation processes.
- Gelling and suspending agent for liquid preparations, ophthalmic solutions, and topical formulations.
- Emulsifying agent that enhances the solubility of poorly soluble active ingredients in pharmaceutical emulsions.
- Sustained-release agent that prolongs drug release in extended-release tablet formulations.
4/ Commercial Products
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