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Triethyl citrate – Plasticizer in film-coated tablet

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    1/ Introduction

    Triethyl citrate is an ester of citric acid and ethanol, widely used in pharmaceutical formulations. It functions as a plasticizer in film coatings, improving flexibility, durability, and preventing cracking of the film. Moreover, triethyl citrate is considered safe, non-toxic, and compatible with various coating polymers.

    2/ Key Advantages

    • High safety profile — non-toxic, non-irritating, and readily metabolized in the body.
    • Compatible with a wide range of film-coating polymers.
    • Excellent oxidative stability — resistant to degradation over time, thereby enhancing product shelf life and stability.
    • Slow evaporation rate, helping maintain film plasticity throughout spraying and drying processes.
    • Low viscosity and good dispersibility in water.  
    • Product complies with USP/EP/BP
    • The manufacturer has EXCIPACT GMP Certificate for Pharma application
    • Stock available at GSP/ GDP warehouse, prompt delivery, competitive price

    3/ Applications

    • Plasticizer in film coating: lowers the glass transition temperature, making the film more flexible, soft, and elastic; reduces the risk of cracking and enhances adhesion to the tablet core.
    • Solvent/carrier in liquid formulations: dissolves poorly water-soluble drugs and excipients, and is used in microemulsion systems.

    4/ Commercial Products

     

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    02-04 Alexandre De Rhodes Street, Sai Gon Ward, Ho Chi Minh City 70000, Vietnam0834560500bm@summ.vn
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    02-04 Alexandre De Rhodes Street, Sai Gon Ward, Ho Chi Minh City 70000, Vietnam0834560500bm@summ.vn
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